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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 68 for pediatric AND surgery

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  1. A Study to Assess the Safety and Pharmacokinetics of Subcutaneously Administered Golimumab, a Human Anti-TNFα Antibody, in Pediatric Patients With Moderate to Severe Active Ulcerative Colitis

    Rochester, MN

  2. NIRS Predict Low Cardiac Output State in Neonates and Infants in Cardiac Surgery

    Rochester, MN

  3. Combination Chemotherapy and Surgery in Treating Young Patients with Wilms Tumor

    Rochester, MN

  4. A Study to Assess Cisplatin and Combination Chemotherapy in Treating Children and Young Adults with Hepatoblastoma or Liver Cancer After Surgery

    Rochester, MN

  5. Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

    Rochester, MN

  6. A Study to Evaluate Anterior Vertebral Body Tethering (AVBT) Zimmer Biomet Tether System or Dynesys System to Treat Pediatric Scoliosis

    Rochester, MN, Minneapolis, MN, Eau Claire, WI, La Crosse, WI

  7. A Study to Design a Questionnaire to Measure the Hearing Handicap for the Pediatric Population

    Rochester, MN

  8. A Study of Speech Perception for Children with Cochlear Implants

    Rochester, MN

  9. A Study of Glembatumumab Vedotin for Treating Patients with Recurrent or Treatment Resistant Osteosarcoma

    Rochester, MN

  10. Covered CP Stents for the Prevention or Treatment of Aortic Wall Injury Associated With Coarctation of the Aorta

    Rochester, MN

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