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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 68 for pediatric AND surgery

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  1. Safety of BM-MNC Intramyocardial Delivery in Ebstein RV

    Rochester, MN

  2. Risk-Based Therapy in Treating Younger Patients with Newly Diagnosed Liver Cancer

    Rochester, MN

  3. A Phase 2 Study of Anti-PD-L1 Antibody Atezolizumab in Alveolar Soft Part Sarcoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. Umbilical Cord Blood Collection and Processing for Congenital Heart Disease

    Rochester, MN

  5. A Study of Ovarian Tissue Freezing for the Preservation of Fertility in Children

    Rochester, MN

  6. Testicular Tissue Cryopreservation in Children

    Rochester, MN

  7. A Study to Evaluate Perceptions of Midline Sternotomy Scar in Children and Young Adults

    Rochester, MN

  8. A Study to Develop Liquid Biopsy for Pediatric Brain Tumor Patients

    Rochester, MN

  9. Outcomes after Fontan Operation

    Rochester, MN

  10. National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

    Rochester, MN

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