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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 41 for migraine

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  1. White Matter Hyperintensities in Migraine: A Multi-modal Imaging Project to Classify Disease Pathology

    Scottsdale/Phoenix, AZ

  2. A Study to Compare the Effectiveness of Using Tints or Thin-Films on Eye Glass Lens to Reduce Light Sensitivity for Patients with Chronic Migraine

    Scottsdale/Phoenix, AZ

  3. A Study to Evaluate the Safety and Effectiveness of GORE® CARDIOFORM Septal Occluder to Treat Migraine Headaches

    Scottsdale/Phoenix, AZ

  4. Understanding Post-Traumatic Headache: Forward Translation of a Posttraumatic Headache Animal Model to Posttraumatic Headache in the Human

    Scottsdale/Phoenix, AZ

  5. A Study of Sphenopalatine Ganglion Stimulation for the Treatment of Chronic Cluster Headache

    Jacksonville, FL

  6. Sphenopalatine Ganglion Stimulation for the Treatment of Chronic Cluster Headache

    Scottsdale/Phoenix, AZ

  7. OnabotulinumtoxinA as a Treatment for Hemiplegic Migraine

    Rochester, MN

  8. A Study of Speech Changes as Predictors of Migraine Attack Onset

    Scottsdale/Phoenix, AZ

  9. A Study of the Individualized Prediction of Migraine Attacks Using a Mobile Phone App and Fitbit Data

    Scottsdale/Phoenix, AZ

  10. A Study to Evaluate the Safety of Fremanezumab in Patients with Migraine in Routine Clinical Practice

    Rochester, MN

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