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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 41 for migraine

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  1. The MOTS (Medication Overuse Treatment Strategy) Trial

    Scottsdale/Phoenix, AZ, Rochester, MN

  2. Evaluation of ALD403 (Eptinezumab) in the Prevention of Chronic Migraine

    Scottsdale/Phoenix, AZ

  3. Efficacy, Safety, and Tolerability of Oral Ubrogepant in the Acute Treatment of Migraine

    Scottsdale/Phoenix, AZ

  4. A Non-Invasive Neuromodulation Device for Prevention of Episodic Migraine Headache

    Scottsdale/Phoenix, AZ

  5. Verapamil vs. Sertraline for Vestibular Migraine & Chronic Subjective Dizziness

    Scottsdale/Phoenix, AZ, Rochester, MN

  6. An Extension Study to Evaluate the Long-Term Safety and Tolerability of Ubrogepant in the Treatment of Migraine

    Scottsdale/Phoenix, AZ

  7. A Study of Non-invasive Vagus Nerve Stimulation for the Prevention of Migraines

    Scottsdale/Phoenix, AZ

  8. The Childhood and Adolescent Migraine Prevention Study

    Rochester, MN

  9. MRI Study To Identify Functional and Structural Changes That Correlate with Patient Improvement When Imaging the Brain Pre-and-Post Erenumab

    Scottsdale/Phoenix, AZ

  10. A Study to Evaluate Intravenous Erenumab in Patients with Status Migrainosus

    Scottsdale/Phoenix, AZ

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