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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 70 for migraine

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  1. Transnasal Cooling for Migraine

    Scottsdale/Phoenix, AZ

  2. Occipital Nerve Stimulation (ONS) for Migraine: OPTIMISE

    Scottsdale/Phoenix, AZ

  3. Assessment of LBR-101 In Chronic Migraine

    Scottsdale/Phoenix, AZ

  4. A Study Using Botulinum Toxin Type A as Headache Prophylaxis in Adolescents with Chronic Migraine

    Rochester, MN

  5. Metformin for the Prevention of Episodic Migraine (MPEM)

    Scottsdale/Phoenix, AZ

  6. Digital Biomarkers for Objectively and Remotely Monitoring Migraine

    Scottsdale/Phoenix, AZ

  7. A Multicenter Assessment of ALD403 in Chronic Migraine

    Scottsdale/Phoenix, AZ

  8. Rizatriptan for Episodic Dizziness in Vestibular Migraine

    Rochester, MN

  9. A Multicenter Assessment of LBR-101 in High Frequency Episodic Migraine

    Scottsdale/Phoenix, AZ

  10. The MOTS (Medication Overuse Treatment Strategy) Trial

    Scottsdale/Phoenix, AZ, Rochester, MN

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