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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 70 for migraine

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  1. A Study of King-Devick test (KDT) and Visual Contrast Sensitivity (VCS) Test Can Detect Migraine Attacks

    Scottsdale/Phoenix, AZ

  2. Prospective Comparison of Methods for Assessment for Headache Directionality

    Scottsdale/Phoenix, AZ

  3. A Study of Structural and Functional Brain Characteristics in Patients with Headache Disorders Using Neuroimaging

    Scottsdale/Phoenix, AZ

  4. Various Visual Symptoms in Children

    Rochester, MN

  5. A Study to Evaluate Droperidol Use in the Emergency Department and the Effect on QTc

    Rochester, MN

  6. A Study to Develop an MRI (Magnetic Resonance Imaging) Based System to Identify Persistent Posttraumatic Headaches as Different from Chronic Migraines

    Scottsdale/Phoenix, AZ

  7. A Study to Develop a Large-Scale Long-Term Database of Headache Disorders

    Scottsdale/Phoenix, AZ

  8. Smartphone-based Migraine Interactive Care Plan Effect in Primary Care

    Rochester, MN

  9. Pegylated Interferon Alfa-2a Salvage Therapy in High Risk Polycythemia Vera (PV) or Essential Thrombocythemia (ET)

    Scottsdale/Phoenix, AZ

  10. Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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