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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 28 for lewy body

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  1. A Study to Evaluate Caregiver Connections via Technology for Patients with Alzheimer's and Other Types of Dementia

    Rochester, MN

  2. Fighting Parkinson’s Disease and Lewy Body Dementia with Anti-Diabetic Medications to

    Jacksonville, FL

  3. Blinded Comparison of Different Alpha-Synuclein Seeding Assays as Cutaneous Biomarkers of Lewy Body Dementias

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. A Study to Identify Factors Predicting End-of-life Dementia with Lewy Bodies and End-of-life Experiences

    Rochester, MN

  5. A Study of Change in Imaging Biomarkers of Dementia with Lewy Bodies (DLB) and Associations with Cognitive and Functional Decline

    Jacksonville, FL, Rochester, MN

  6. Study to Evaluate the Pathophysiology of Multiple System Atrophy, Parkinson's Disease, Parkinson's Disease with Autonomic Failure and Dementia with Lewy Bodies Using Microneurographic Recordings of Muscle Sympathetic Nerve Activity

    Rochester, MN

  7. A Study to Collect Blood DNA Samples from Patients with Clinically Diagnosed Alzheimers Disease, Lewy Body Disease, and Frontotemporal Degeneration

    Rochester, MN

  8. A Study to Create a Diagnostic Test for Patients with Parkinson's disease, Multiple System Atrophy, Dementia with Lewy bodies and Pure Autonomic Failure

    Rochester, MN

  9. Anti-Bullous Pemphigoid Antibodies in Patients with Neurological Disease

    Rochester, MN

  10. A Study of the Brain & Body Donation Program

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