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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 22 for lewy body

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  1. A Study Evaluating Nelotanserin for Treatment of Visual Hallucinations in Subjects with Lewy Body Dementia

    Rochester, MN

  2. Study Evaluating Intepirdine (RVT-101) in Subjects With Dementia With Lewy Bodies: The HEADWAY-DLB Study

    Jacksonville, FL, Rochester, MN

  3. Long-Term Extension Study of Intepirdine (RVT-101) in Subjects With Dementia With Lewy Bodies:

    Jacksonville, FL, Rochester, MN

  4. A Study of Armodafinil for Patients with Dementia with Lewy Bodies

    Rochester, MN

  5. Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder

    Rochester, MN

  6. A Study of LY3154207 in Participants With Parkinson's Disease Dementia or Dementia with Lewy Bodies

    Scottsdale/Phoenix, AZ

  7. A Study to Evaluate the Cognitive Effects of Oral p38 Alpha Kinase Inhibitor Neflamapimod in Dementia with Lewy Bodies

    Rochester, MN

  8. DaTSCAN Imaging in Aging and Neurodegenerative Disease

    Rochester, MN, Jacksonville, FL

  9. Study Evaluating Nelotanserin for Treatment of REM Sleep Behavior Disorder in Subjects With Dementia (DLB or PDD)

    Rochester, MN

  10. A Study to Identify Factors Predicting End-of-life Dementia with Lewy Bodies and End-of-life Experiences

    Rochester, MN

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