Mayo Advancing Research Engagement In ADRD Study In Jacksonville (MAREAS Jax)

Overview

About this study

The purpose of this study is to advance recruitment of HRP cohorts (UH2) by developing/deploying outreach, recruitment, and engagement best practices for HRP in Jacksonville, Florida, through a bilingual (English-Spanish) research team, supported by community ambassador teams (CAT) and an external advisory board (EAB) including experts in social risk factors and ADRD research.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:             

  • Community-dwelling HL and BA individuals from the Jacksonville metro area

  • Age 45 years-old and older

  • Cognitively normal or mildly impaired at study entry (global CDR® 0-0.5)

 

Exclusion Criteria:

  • Individuals with cognitive impairment > CDR® 0.5 are not eligible.

  • Individuals with neurological diseases that may affect cognition such as epilepsy, multiple sclerosis, severe head injury, motor neuron disease, Parkinson disease.

  • Individuals with psychiatric diseases that could affect cognition or longitudinal participation, including bipolar disorder, schizophrenia, uncontrolled depression or anxiety.

  • Individuals with medical illnesses that would prevent them from participating in a longitudinal study such as active cancer, significant heart, lung, kidney and other system illness.

  • Individuals chronically using medications likely to affect cognition (e.g., scheduled narcotics).

  • Inability to comply with imaging studies (brain MR, PET—amyloid, tau)

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 12/22/2025. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Christian Lachner, M.D.

Open for enrollment

Contact information:

Christian Lachner

9049537103

lachner.christian@mayo.edu

More information

Publications

Publications are currently not available