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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 71-80 of 123 for knee

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  1. A Study ofOutcomes of Patient Specific Implants and Instrumentation Versus Off the Shelf Total Knee Arthroplasty

    Jacksonville, FL

  2. A Study to Evaluate the Effectiveness of Digital Home-Exercise Therapy for Patients with Non-surgical Knee Injuries

    Rochester, MN, Minneapolis, MN

  3. A Study of Outcomes from the Use of Tranexamic Acid in Revision Total Joint Arthroplasty

    Rochester, MN

  4. Metabolomic Profiling of Patients Undergoing Total Knee Arthroplasty

    Jacksonville, FL

  5. Non-invasive Hemoglobin Monitoring in Patients Undergoing Outpatient TJA

    Rochester, MN

  6. A Study to Collect Clinical Outcomes in Patients after Knee Arthroplasty

    Rochester, MN

  7. Immunoregulatory Factor Analysis in Platelet Rich Plasma (PRP) to Treat Knee Osteoarthritis (OA)

    Scottsdale/Phoenix, AZ

  8. A Study Comparing the Results of Using Irradiated versus Non-Irradiated Grafts for ACL (Knee Ligament) Reconstruction

    Rochester, MN

  9. Revision Knee Replacement for Flexion Instabiity

    Rochester, MN

  10. A Study of Genes Responsible for Joint Contractures in People Who Have Had Total Joint Surgery

    Rochester, MN

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