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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-16 of 16 for hiv

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  1. A Study of Blood Mononuclear Cells from HIV Patients and Control Subjects

    Rochester, MN

  2. Collection of Blood Samples from a Population at Low Risk for HIV Infection

    Rochester, MN

  3. Epigenomic Biomarkers of HIV-Associated Hepatocellular Cancer in Nigeria

    Rochester, MN

  4. A Study to Screen HIV and Syphilis Screening Using Dried Blood Spot Testing

    Rochester, MN

  5. Lymphoid Tissue Examination

    Rochester, MN

  6. Laboratory Assay Optimization 2.0

    Rochester, MN

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