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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 16 for hiv

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  1. Analytic Treatment Interruption (ATI) to Assess HIV Cure

    Rochester, MN

  2. A Study of the Effect of Ixazomib on the Reservoir of T Cells Infected with HIV DNA

    Rochester, MN

  3. A Study to Evaluate the Effects of Losartan to Reduce Inflammation and Fibrosis Endpoints in Patients with HIV

    Rochester, MN

  4. A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of ABBV-181 (Budigalimab) in Adult Participants With HIV-1

    Rochester, MN

  5. Allogeneic Transplant in HIV Patients (BMT CTN 0903)

    Scottsdale/Phoenix, AZ, Rochester, MN

  6. A Study to Evaluate the Effectiveness and Safety of Remdesivir to Treat Coronavirus Disease 2019 in an Outpatient Setting

    Rochester, MN

  7. A Study to Evaluate the Long-term Safety and Tolerability of Inhaled LIQ861(Treprostinil) in Pulmonary Arterial Hypertension Patients

    Jacksonville, FL

  8. A Study to Evaluate the Effectiveness and Safety of Ralinepag To Improve Treatment Outcomes in Peripheral Arterial Hypertension (PAH) Patients

    Scottsdale/Phoenix, AZ

  9. A Study of Total Joint Arthroplasty in Patients with Human Immunodeficiency Virus (HIV)

    Rochester, MN

  10. Characterizing HIV-related Diastolic Dysfunction

    Rochester, MN

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