Lymphoid Tissue Examination


About this study

The purpose of this study is to study HIV infected individuals or others who have had another infection or inflammatory condition that may affect the content or structure of lymph nodes or may have none of these conditions and the sample will be used as a normal control.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adult (≥18 years of age) donors recruited for lymphoid tissue biopsy by the principal investigator, co-investigators, study coordinators, Infectious Disease clinic nurses, or clinic phlebotomists.
  • Required to have a platelet count >50,000/mm³ documented in the medical record within 30 days prior to the procedure.
  • Eligible participants may have HIV infection, or another infection or inflammatory condition that may affect the content or structure of lymph nodes, or no known disease if used as a normal control. 

Exclusion Criteria:

  • Inability to provide informed consent
  • Self-reported or clinically documented pregnancy
  • Known allergy to local anesthetic
  • Significant bleeding diatheses
  • Active bacterial infection
  • Any other condition that in the opinion of the principal investigator would increase the risk of the adverse events associated with the surgical procedure.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Nathan Cummins, M.D.

Open for enrollment

Contact information:

Nathan Cummins M.D.


More information


Publications are currently not available

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