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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 191-200 of 840 for cardiovascular

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  1. A Study of the Delivery of Yamani-15/5 Chemical Solution for Peripheral Artery Disease

    Jacksonville, FL

  2. A Study to Evaluate the Safety and Tolerability of LCZ696 Followed by a 52-week Study of LCZ696 Compared With Enalapril in Pediatric Patients with Heart Failure

    Rochester, MN

  3. A Study of Vutrisiran (ALN-TTRSC02) in Patients with Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)

    Rochester, MN

  4. Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI)

  5. Safety and Efficacy Study of Lotus Valve for Transcatheter Aortic Valve Replacement

    Rochester, MN

  6. Low Cost QTc Meter for Long QT Syndrome Screening in Primary Care

    Rochester, MN

  7. PORtopulmonary Hypertension Treatment wIth maCitentan ─ a randOmized Clinical Trial

    Scottsdale/Phoenix, AZ

  8. Understanding Outcomes With the EMBLEM™ S-ICD in Primary Prevention Patients With Low Ejection Fraction

    Scottsdale/Phoenix, AZ

  9. A Study for the Development of a Low Cost QTc Meter for Long QT Syndrome Screening in Primary Care

    Rochester, MN

  10. A Study of the Effects of Decreasing the Lasix Dose on the Cardiorenal System

    Rochester, MN

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