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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 55 for als

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  1. Study of Xavier Electromyographic Wheelchair Control for Limited Mobility Patients

    Jacksonville, FL

  2. Effects of Oral Levosimendan (ODM-109) on Respiratory Function in Patients With ALS

    Rochester, MN

  3. A Study of GDC-0134 to Determine Initial Safety, Tolerability, and Pharmacokinetic Parameters in Participants With Amyotrophic Lateral Sclerosis

    Jacksonville, FL

  4. A Compassionate Use Study to Administer NurOwn® (Autologous Mesenchymal Stem Cells Secreting Neurotrophic Factors) to Treat Amyotrophic Lateral Sclerosis (ALS)

    Rochester, MN

  5. A Study of the Effect of Ezogabine on Motor Neuron Excitability in Patients with Amyotrophic Lateral Sclerosis

    Jacksonville, FL

  6. A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB100 Administered Orally to Adults With Amyotrophic Lateral Sclerosis

    Jacksonville, FL

  7. A Study to Evaluate Intrathecal Autologous Adipose-derived Mesenchymal Stromal Cells for Amyotrophic Lateral Sclerosis

    Rochester, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL

  8. A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Effect on Disease Progression of BIIB078 in Amyotrophic Lateral Sclerosis (ALS) Patients

    Jacksonville, FL

  9. A Study to Evaluate MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients with Amyotrophic Lateral Sclerosis (ALS)

    Jacksonville, FL, Rochester, MN

  10. A Dose-escalation Safety Trial for Intrathecal Autologous Mesenchymal Stem Cell Therapy in Amyotrophic Lateral Sclerosis

    Rochester, MN

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