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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 46 for als

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  1. Diaphragm Pacing System (DPS) in Participants with Amyotrophic Lateral Sclerosis (ALS)

    Jacksonville, FL

  2. A Study for Patients Who Completed VITALITY-ALS (CY 4031) VIGOR-ALS

    Jacksonville, FL

  3. Safety and Efficacy of Repeated Administrations of NurOwn® in ALS Patients

    Rochester, MN

  4. A Study of the Safety of Mesenchymal Stem Cells for Treatment of One Patient with Amyotrophic Lateral Sclerosis (ALS)

    Rochester, MN

  5. Effects of Oral Levosimendan (ODM-109) on Respiratory Function in Patients With ALS

    Jacksonville, FL

  6. Intrathecal Autologous Adipose-derived Mesenchymal Stromal Cells for Amyotrophic Lateral Sclerosis (ALS)

    Rochester, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL

  7. A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS)

    Jacksonville, FL

  8. Perampanel Transcranial Magnetic Stimulation (TMS) in Amyotrophic Lateral Sclerosis (ALS)

    Jacksonville, FL

  9. A Study of the Safety and Effectiveness of NP001 for Patients with Amyotrophic Lateral Sclerosis (ALS) and Systemic Inflammation

    Jacksonville, FL

  10. A Study of the Safety and Effectiveness of NP001 for Patients with Amyotrophic Lateral Sclerosis (ALS) and Systemic Inflammation

    Scottsdale/Phoenix, AZ

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