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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 55 for als

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  1. Phase 2, Randomized, Double Blind, Placebo Controlled Multicenter Study of Autologous MSC-NTF Cells in Patients with ALS

    Rochester, MN

  2. A Study to Evaluate the Effects of Oral Levosimendan (ODM-109) on Respiratory Function in Patients With ALS

    Jacksonville, FL

  3. An Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of BIIB067 in Adults With Inherited Amyotrophic Lateral Sclerosis (ALS) (VALOR (Part C))

    Jacksonville, FL, Rochester, MN

  4. A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS)

    Rochester, MN

  5. A Study to Explore the Safety and Tolerability of Acthar in Patients With Amyotrophic Lateral Sclerosis

    Jacksonville, FL

  6. Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a Year

    Jacksonville, FL

  7. A Study to Evaluate the Long-Term Effectives on ALS Disease Progression of BIIB067

    Jacksonville, FL, Rochester, MN

  8. Effects of Oral Levosimendan (ODM-109) on Respiratory Function in Patients With ALS

    Rochester, MN

  9. Humanitarian Device Exemption Post-Approval Study of NeuRx Diaphragm Pacing System for Amyotrophic Lateral Sclerosis

    Jacksonville, FL

  10. A Study to Assess the Efficacy and Safety of H.P. Acthar® Gel in the Treatment of Subjects With Amyotrophic Lateral Sclerosis

    Scottsdale/Phoenix, AZ

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