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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 55 for als

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  1. A Study to Determine the Effectiveness and Safety of Oral Edaravone Administered in Subjects with Amyotrophic Lateral Sclerosis

    Jacksonville, FL, Rochester, MN

  2. A Study to Evaluate ALZT-OP1a in Subjects with Mild-to-Moderate Amyotrophic Lateral Sclerosis

    Jacksonville, FL

  3. Expanded Access Program with Tirasemtiv for the Treatment of Amyotrophic Lateral Sclerosis (ALS)

    Jacksonville, FL

  4. A Study to Assess FLX-787 in Subjects With Motor Neuron Disease Experiencing Muscle Cramps.

    Jacksonville, FL

  5. A Study to Assess FLX-787 in Subjects With Motor Neuron Disease Experiencing Muscle Cramps

    Scottsdale/Phoenix, AZ

  6. A Study to Assess The Amyotrophic Lateral Sclerosis (ALS) Patient Experience

    Jacksonville, FL

  7. Markers of Inflammation in Patients with Motor Neuron Disease (ALS and ALS Variants)

    Scottsdale/Phoenix, AZ

  8. A Study of Deep Phenotyping in Patients With ALS

    Rochester, MN

  9. A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers

    Jacksonville, FL

  10. Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders

    Jacksonville, FL

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