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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 91 for COVID

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  1. A Study to Compare Saliva and Swab Specimens in Detection of COVID Severe Acute Respiratory Syndrome

    Albert Lea, MN, Austin, MN, Red Wing, MN, Owatonna, MN, Rochester, MN, Mankato, MN

  2. A Study to Evaluate the Effectiveness of Merimepodib in Adult Patients with Advanced COVID-1

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  3. A Study to Evaluate the Feasibility of Rapid COVID-19 Testing in Disadvantaged Populations

    Rochester, MN

  4. A Study to Evaluate Positive SARS-CoV-2 Antibodies in Subjects with Bipolar Disorder

    Rochester, MN

  5. Losartan for Outpatients on COVID-19

    Rochester, MN

  6. A Study to Evaluate Convalescent Plasma to Stem Coronavirus

    Scottsdale/Phoenix, AZ

  7. A Study to Evaluate AntiThrombotic Therapy to Lessen Complications of COVID-19 (Enrolling by Invitation Only)

    Rochester, MN

  8. A Study to Evaluate Clazakizumab in Patients with Life-threatening COVID-19 Infection (Enrolling by Invitation Only)

    Scottsdale/Phoenix, AZ

  9. A Study to Generate Algorithms for Early Prediction of Aggressive Progression and Hospitalization in Patients Diagnosed with SARS-CoV-2/COVID-19 Infection

    Rochester, MN

  10. A Study to Assess the Safety, Tolerability and Effectiveness of Monoclonal Antibodies to Treat Hospitalized Patients with COVID-19

    Rochester, MN

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