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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 118 for COVID

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  1. A Study to Evaluate Agents to Treat Moderately or Severely Ill Patients with Severe Acute Respiratory Syndrome Coronavirus 2

    Rochester, MN

  2. A Study to Evaluate Rivaroxaban to Reduce Risk of Major Venous and Arterial Thrombotic Events, Hospitalization and Death in Medically Ill Outpatients with Acute COVID-19 Infection

    Rochester, MN

  3. A Study to Assess Steroid Dosing by bioMARker Guided Titration in Critically Ill Patients With Pneumonia

    Rochester, MN

  4. Health Coaching and Recovery from Post-COVID Syndrome in Adolescents

    Rochester, MN

  5. A Study to Evaluate the Effectiveness and Safety of Remdesivir to Treat Coronavirus Disease 2019 in an Outpatient Setting

    Rochester, MN

  6. RECOVER-VITAL: Platform Protocol to Measure the Effects of Antiviral Therapies on Long COVID Symptoms (RECOVER-VITAL)

    Rochester, MN

  7. COVID-19 Cytokine Assay

    Rochester, MN

  8. Antibodies against COVID (enrolling by invitation)

    Rochester, MN

  9. Development of Potential COVID-19 Vaccine and Serological Assay

    Rochester, MN

  10. COVID-19 Residual Biobank (Enrolling by Invitation Only)

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

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