A Study to Compare Saliva and Swab Specimens in Detection of COVID Severe Acute Respiratory Syndrome


About this study

Compare Patient-Collected Saliva and Health Care Worker Collected Nasopharyngeal and Nasal Mid-Turbinate Swabs for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Detection by nucleic acid amplification testing (NAAT). All tests will be performed using previously-validated, EUA NAATs that are available in the Clinical Microbiology laboratory, including the Mayo Clinic laboratory developed test (LDT).





Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Up to 500 patients will be recruited for this study. Patients presenting for drive-through or walk-in tent specimen collection for RT-PCR testing for SARS-CoV-2 at one or more of the following SE or SW Minnesota testing sites would be enrolled:



Mankato Eastridge

101 Martin Luther King Jr. Drive


New Prague

212 10th Ave NE



800 Medical Center Drive



2200 26th St NW



510 2nd St NW


Albert Lea

1705 SE Broadway Ave


Red Wing

1407 West 4th Street


The drive-thru or tent collection sites would be selected based upon testing volumes and percent positive tests in the week preceding study commencement, in order to maximize the number of positive SARS-CoV-2 PCR results.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Bobbi Pritt, M.D.

Closed for enrollment

More information


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