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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 111 for COVID

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  1. A Study to Evaluate MesilatE for Treating Hospitalized Patients with COVID-19 (Enrolling by Invitation Only)

    Jacksonville, FL, Scottsdale/Phoenix, AZ

  2. A Study to Evaluate the Safety and Efficacy of Tocilizumab in Patients With Severe COVID-19 Pneumonia (enrollment by invitation only)

    Rochester, MN

  3. A Study to Investigate Intravenous Tocilizumab in Patients with Moderate-to-Severe COVID-19 Pneumonia (enrolling by invitation only)

    Jacksonville, FL, Scottsdale/Phoenix, AZ

  4. Study to Evaluate the Effectiveness and Safety of Remdesivir in Participants with Severely Reduced Kidney Function Who Are Hospitalized for Coronavirus Disease 2019

    Jacksonville, FL, Rochester, MN

  5. Immunological Consequences of COVID-19 Vaccination in Patients with Rheumatic Diseases

    Rochester, MN

  6. Use of Combined Prone Positioning and High-Flow Nasal Cannula, and Non-invasive Positive Pressure Ventilation to Prevent Intubation in COVID-19 Infection (enrolling by invitation only)

    Rochester, MN

  7. A Study to Evaluate At Home Administration of Pertuzumab Combined with Trastuzumab to Treat Patients with HER2-Positive Breast Cancer During COVID-19 Pandemic

    Jacksonville, FL, Rochester, MN

  8. Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine

    Rochester, MN

  9. A Study to Evaluate a Resiliency Program for Healthcare Professionals During a Pandemic

    Rochester, MN

  10. A Study to Evaluate the Efficacy and Safety of Colchicine on Coronavirus SARS-CoV2 Positive Adults

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

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