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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 26 for Pain Medicine

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  1. A Study of Quality of Life and Pain Control Before and After Endovascular Renal Denervation in Individuals with Refractory Kidney Pain

    Rochester, MN

  2. Ultrasound Guided Transversus Abdominis Plane (TAP) vs. Trigger Point Injection (TPI) for Abdominal Wall Pain

    Rochester, MN

  3. A Phase IV Post Approval Clinical Study of ExAblate Treatment of Metastatic Bone Tumors for the Palliation of Pain

    Rochester, MN

  4. Cervical Spinal Cord Stimulation in Cerebral Vasospasm

    Jacksonville, FL

  5. A Study to Evaluate Patient Experience Comparing Tonic vs. Burst Spinal Card Stimulation for Chronic Pain

    Jacksonville, FL

  6. A Study of Lofexidine for Rapid Opioid Tapering in Adults

    Rochester, MN

  7. A Study of the Use of Shear Wave Elastography with an Ultrasound Scanner to Measure Myofascial Trigger Points

    Rochester, MN

  8. A Study of An Internet-based Pain Self-management Program for Persons with Acute Recurrent and Chronic Pancreatitis Pain

    Rochester, MN

  9. A Study to Compare HF10 Therapy Combined with Conventional Medical Management (CMM) to CMM Alone in the Treatment of Non-Surgical Refractory Back Pain

    Rochester, MN

  10. A Study to Evaluate Prevalence of Hypogonadism in Patients with Chronic Pain

    Jacksonville, FL

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