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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 67 for Nephrology and Hypertension

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  • Study status: Open/Status Unknown
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  1. A Study to Promote Shared Decision Making of Treatment Choices in Patients who have Advanced Kidney Disease

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. A Study to Evaluate Bardoxolone Methyl in Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD)

    Rochester, MN

  3. A Study to Evaluate the Safety and Effectiveness of OMS721 in Patients with Immunoglobulin A (IgA) Nephropathy

    Scottsdale/Phoenix, AZ, Rochester, MN

  4. Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Non-Dialysis (ASCEND-ND)

    Jacksonville, FL

  5. HELP-HY: Health Education and sLeep Program in HYpertension

    Rochester, MN

  6. Statins and CPAP in Adipose Tissue of OSA

    Rochester, MN

  7. Post Approval Study for Treatment of Drug-resistant Adult Primary FSGS Using the LIPOSORBER® LA-15 System

    Rochester, MN

  8. Inflammation and Stem Cells in Diabetic and Chronic Kidney Disease

    Rochester, MN

  9. Senescence in Chronic Kidney Disease

    Rochester, MN

  10. A Study to Evaluate the Effectiveness of Nicotinamide Riboside and Pterostilbene Treatment to Protect the Kidneys in Patients with Complex Aortic Aneurysm Repair and Aortic Arch Reconstruction

    Rochester, MN

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