Family History

  • Participants are asked to provide their family health history for the conditions studied in eMERGE IV, using an online tool called MeTree developed at Duke University.
  • Participants are asked about the presence of the conditions in their first-degree relatives, and family history is used to help assess risk for some of the conditions.
  • For breast cancer, second-degree relatives are also included, and family history is used in calculating the BOADICEA score.
  • For the following conditions, family history is displayed on the GIRA report:
    • Asthma
    • Atrial Fibrillation
    • Breast Cancer (women)
    • Chronic Kidney Disease
    • Coronary Heart Disease
    • Hypercholesterolemia
    • Obesity/BMI
    • Prostate Cancer (men)
    • Type I Diabetes
    • Type II Diabetes
  • For the following conditions, having one or more close family members with the condition triggers a high-risk report:
    • Atrial Fibrillation
    • Breast cancer (women)
    • Chronic Kidney Disease
    • Coronary Heart Disease
    • Prostate Cancer (men)