Infectious Diseases Research

Below are current clinical trials.

269 studies in Infectious Diseases Research
(all studies, either open or closed).

Filter this list of studies by location, status and more.

1. A Study to Evaluate Near-Patient Tests for the Direct Detection of SARS-CoV-2

   Scottsdale/Phoenix, Ariz.

   The pupose of this study is to evaluate near-patient methods, including both point of care (POC) and patient-performed testing.

2. Efficacy and Safety of COVID-19 Vaccine in Cancer Patients

   Jacksonville, Fla.

   We hypothesize that cancer patients on cytotoxic chemotherapy which affect immune response may not mount adequate immune response to COVID-19 vaccines.

   Aims, purpose, or objectives:

   1. To determine the antibody response to COVID-19 vaccine after vaccination.
   2. To assess the adverse events of COVID-19 vaccines in cancer patients.
   3. To determine the incidence and severity of COVID-19 infection after the vaccination.

3. Long-term Effects of SARS-CoV-2

   Jacksonville, Fla.

   The purpose of this study is to perform an ambi-directional clinical, neurological, cognitive, functional, and blood boimarker study of hospitalized patients with and without COVID-19.

    

    

    

4. Efficacy and Safety of Maribavir in Transplant Recipients With Cytomegalovirus (CMV) Infections That Are Refractory or Resistant to Treatment

   Rochester, Minn.

   The purpose of this study is to determine if an investigational treatment (Maribavir) is safe and effective in treating transplant recipient patients with cytomegalovirus (CMV) infections that are refractory or resistant to treatment.

5. Analysis of Blood and Urine for Microbial Pathogen Discovery and Undiagnosed Infection

   Rochester, Minn.

   The aim of this study is to identify difficult to diagnose microbial pathogens causing infections using blood or urine for identification of bacteria, viruses, fungi or parasites that are not detectable or are difficult to detect using current diagnostic techniques.

6. PC945 Prophylaxis or Pre-emptive Therapy Against Pulmonary Aspergillosis in Lung Transplant Recipients

   Jacksonville, Fla.

   The purpose of this study is to evaluate the safety and tolerability of PC945 for the prevention of fungal aspergillus infections in the lung in patients who have received a lung transplant.

7. SER-109 Versus Placebo to Prevent Recurrent Clostridium Difficile Infection (RCDI)

   Rochester, Minn.

   The study will involve administering the study drug as a single dose of study drug or placebo. This study is designed to demonstrate the superiority of the experimental drug versus placebo in adult patients with recurrent CDI.

8. A Study to Evaluate Diagnostic Accuracy of the Controlled Attenuation Parameter(CAP) Measured by FibroScan® in Patients Scheduled for a Liver Biopsy

   Rochester, Minn.

   We purpose of this study is to evaluate the diagnosis accuracy of the Controlled Attenuation Parameter (CAP) measured by FibroScan® (both with M and XL probes) in all patients who are undergoing liver biopsy for any liver disease.  

9. Voice Signal PASC Study

   Rochester, Minn.

   The purpose of this study is to remotely use the Ellipsis Health (EH) voice analysis technology to record the speech patterns and content of individuals with a recent diagnosis of Coronavirus-19 (COVID-19) presenting to the post-COVID-19 clinic at Mayo Clinic, to validate its use as a tool to screen for major depressive disorder (MDD) and generalized anxiety disorder (GAD) against gold-standard questionnaires used in clinical practice namely the PHQ-9 and GAD-7

10. A Study to Assess the Burden of Respiratory Syncytial Virus Infections in Older Adults in a North American Community

    Rochester, Minn.

    The primary purpose of this study is to estimate the incidence rate of confirmed respiratory syncytial virus (RSV) (and other confirmed respiratory viruses) infections and associated adverse outcomes.