Infectious Diseases Research

Below are current clinical trials.

269 studies in Infectious Diseases Research
(all studies, either open or closed).

Filter this list of studies by location, status and more.

1. A Study to Assess the Culture, PCR, Serology and Symptoms of COVID-19

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to understand when patients are shedding active COVID virus RNA as detectable by viral culture, and if there are any correlates of the cessation of active viral shedding, such as presence of certain immunoglobulins.

   Additionally, this study will take a discovery approach to the immune response to better understand how the body recovers or worsens during disease, and if there are opportunities to use that knowledge to develop treatments.

    

2. Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCHCD3)

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to confirm the effectiveness of RBX2660 as compared to a placebo in preventing recurrent episodes of Clostridium difficile Infection (CDI) through 8 weeks.

    

    

    

3. A Study to Evaluate Near-Patient Tests for the Direct Detection of SARS-CoV-2

   Scottsdale/Phoenix, Ariz.

   The pupose of this study is to evaluate near-patient methods, including both point of care (POC) and patient-performed testing.

4. Efficacy and Safety of COVID-19 Vaccine in Cancer Patients

   Jacksonville, Fla.

   We hypothesize that cancer patients on cytotoxic chemotherapy which affect immune response may not mount adequate immune response to COVID-19 vaccines.

   Aims, purpose, or objectives:

   1. To determine the antibody response to COVID-19 vaccine after vaccination.
   2. To assess the adverse events of COVID-19 vaccines in cancer patients.
   3. To determine the incidence and severity of COVID-19 infection after the vaccination.

5. Long-term Effects of SARS-CoV-2

   Jacksonville, Fla.

   The purpose of this study is to perform an ambi-directional clinical, neurological, cognitive, functional, and blood boimarker study of hospitalized patients with and without COVID-19.

    

    

    

6. PC945 Prophylaxis or Pre-emptive Therapy Against Pulmonary Aspergillosis in Lung Transplant Recipients

   Jacksonville, Fla.

   The purpose of this study is to evaluate the safety and tolerability of PC945 for the prevention of fungal aspergillus infections in the lung in patients who have received a lung transplant.

7. SER-109 Versus Placebo to Prevent Recurrent Clostridium Difficile Infection (RCDI)

   Rochester, Minn.

   The study will involve administering the study drug as a single dose of study drug or placebo. This study is designed to demonstrate the superiority of the experimental drug versus placebo in adult patients with recurrent CDI.

8. Voice Signal PASC Study

   Rochester, Minn.

   The purpose of this study is to remotely use the Ellipsis Health (EH) voice analysis technology to record the speech patterns and content of individuals with a recent diagnosis of Coronavirus-19 (COVID-19) presenting to the post-COVID-19 clinic at Mayo Clinic, to validate its use as a tool to screen for major depressive disorder (MDD) and generalized anxiety disorder (GAD) against gold-standard questionnaires used in clinical practice namely the PHQ-9 and GAD-7

9. A Study to Assess the Burden of Respiratory Syncytial Virus Infections in Older Adults in a North American Community

   Rochester, Minn.

   The primary purpose of this study is to estimate the incidence rate of confirmed respiratory syncytial virus (RSV) (and other confirmed respiratory viruses) infections and associated adverse outcomes.

10. A Study to Collect Tissue, Fluids, Blood and/or Fungal Samples in Patients with Pulmonary and Extrapulmonary Coccidioidomycosis

    Scottsdale/Phoenix, Ariz.

    The purpose of this study is to create a biorepository of tissue, fluid and fungal specimens for future studies.