A Study to Assess the Burden of Respiratory Syncytial Virus Infections in Older Adults in a North American Community

Overview

About this study

The primary purpose of this study is to estimate the incidence rate of confirmed respiratory syncytial virus (RSV) (and other confirmed respiratory viruses) infections and associated adverse outcomes.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Southeast Minnesota (SEMN: Olmsted County and nearby counties including Dodge, Goodhue, Mower, Fillmore, Winona, and Wabasha,) residents (residency established at least one year prior to consent) aged 50 years or above at the time of consenting.
  • Those who have primary care physician at Mayo Clinic and a history of primary care visits to Mayo Clinic.
  • Those who authorizes use of their medical record for research.
  • Those who provide written consent to participate in the study.

Exclusion Criteria: 

  • Subjects without authorization for use of medical records for research.
  • Those who do not reside in SEMN at the time of enrollment.
  • Those who may go to health care providers other than Mayo Clinic Rochester (eg, Mayo Kasson, Olmsted Medical Center).
  • (This will not be applicable to Phase II study). Those who develop ARI after October 1, 2019 but prior to enrollment and are not able to come in for enrollment and swabbing within 7 days of symptoms.
  • Those who opt out for swab test and other study procedures.
  • Those who cannot ambulate or those who are bedridden (absolute or perhaps relative contraindications to the 6 minute walk such as uncontrolled/unstable cardiovascular, pulmonary, renal, endocrine, immunological or hepatic disorders).
  • Those with known cognitive impairment.
  • Those who had evidence of an ongoing systemic bacterial, fungal, or viral infection within 7 days prior to enrollment.
  • Those who reside out of Olmsted, Dodge, Goodhue, Mower, Fillmore, Winona, and Wabasha County, MN > 2 weeks during winter season the RSV season (Oct-April) and/or > 4 weeks during summer season (May-Sep).
  • Any reason in the opinion of the study PIs that someone would not be able to complete the requirements of the study for safety or other reasons.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Young Juhn, M.D.

Closed for enrollment

Contact information:

Department of Medicine – Clinical Trials Unit

(507) 266-1944

RSTDOMCTU@mayo.edu

More information

Publications

Publications are currently not available
.

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