Clinical Trials
Below are current clinical trials.
269 studies in Infectious Diseases Research (all studies, either open or closed).
Filter this list of studies by location, status and more.
-
Rochester, Minn.
The purpose of this study is to assess influenza vaccine effectiveness (VE) in preventing pandemic influenza virus illness and infection, and to assess the incidence of pandemic influenza virus infection and illness among Health care providers (HCP), first responders (FR) (police, fire, and Emergency Medical Technicians [EMT]) and school personnel (SP).
-
Rochester, Minn., Mankato, Minn., La Crosse, Wis., Eau Claire, Wis., Scottsdale/Phoenix, Ariz.
The study aims to characterize patient factors, such as pre-existing comorbidities, cancer type and treatment, and demographic factors, associated with short- and long-term outcomes of COVID-19, including severity and fatality, in cancer patients undergoing treatment. The study also is aimed to describe cancer treatment modifications made in response to COVID-19, including dose adjustments, changes in symptom management, or temporary or permanent cessation. Lastely, evaluate the association of COVID-19 with cancer outcomes in patient subgroups defined by clinico-pathologic characteristics.
-
Mankato, Minn., Rochester, Minn.
The prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) in the United States (US) is relatively low. However, immigrant populations in the US from Asia and sub-Saharan Africa have substantially higher prevalence than the general population and are consequently at a significant risk for hepatocellular carcinoma (HCC).
-
Rochester, Minn.
The purpose of this study is to extend the previous SERES-004 study in patients who had a recurrence of clostridium difficile infection within the first 8 weeks of participation.
-
Rochester, Minn.
Achilles tendon rupture is a common injury and surgical treatment poses the risk of infection. An infected Achilles tendon is a difficult entity to treat due to a thin surrounding soft tissue envelope as well as poor tendon vascularity. In this retrospective review of cases examined at Mayo Clinic-Rochester, we seek to elucidate the clinical outcomes of patients who have undergone treatment for an infected Achilles tendon.
-
Rochester, Minn.
The purpose of this study is to investigate disease causing and other organisms which athletes may be exposed to while participating in the Summer Olympic Games. The study will also investigate the organism and metabolism environment of stool, blood analysis and presence of abnormal cell structures in Olympic athletes in comparison with other elite athletes.
-
Rochester, Minn.
The purpose of this study is to demonstrate the efficacy and safety of RBX7455 (an oral microbiota based drug) for the treatment of recurrent clostridium difficile infection (CDI) in subjects who have had at least one recurrence after a primary episode (i.e., at least two episodes) and have completed at least two rounds of standard-of-care oral antibiotic therapy. Study subjects will have their diarrhea resolved, i.e., would be having less than 3 watery bowel movements at the time of study enrollment for 48 hours or more.
-
Rochester, Minn.
The purpose of this study is to evaluate treatment of BK polyomavirus with the use of Brincidofovir.
-
Rochester, Minn., Jacksonville, Fla.
The purpose of this study is to assess the experience of low income pregnant women at an inner-city health system with seeking and receiving care.
Significant disparities in health care and birth outcomes are seen in the US during normal times. During COVID-19, limited access to health care resources, social distancing and stay at home orders, and shortages of food and other necessities may exacerbate these disparities.
-
Rochester, Minn.
The purpose of this study is to compare a standard steroid dosing algorithm to a novel biomarker-tailored steroid dosing algorithm for patients receiving corticosteroids for community acquired pneumonia. Patients with severe community acquired pneumonia may benefit from adjunctive corticosteroid therapy. The optimal patient selection, dosing and duration of steroids is unknown.