Data collection, processing and analysis support

Support for cryo-electron microscopy (CryoEM) data collection at Mayo Clinic and Hormel Institute

The Structural Biology Core houses a 200-kilovolt (kV) Glacios 2 cryogenic transmission electron microscope used for automated grid screening and data collection. To improve throughput, on-the-fly data processing with CryoSPARC Live enables real-time evaluation of data quality.

We have partnered with the Hormel Institute to optimize the use of Mayo Clinic's 200-kV Glacios 2 cryogenic transmission electron microscope and the Hormel Institute's two 300-kV Titan Krios cryogenic transmission electron microscopes.

Support for data processing and analysis

The Structural Biology Core offers access to a graphics processing unit-based high-performance computing cluster and software for cryoEM data analysis. In the future, full data analysis services aimed at structure determination will be available to Mayo researchers.

For consultation or questions regarding structural biology projects and services, submit your request with this intake form (must be logged into the Mayo Clinic network).