Overview
The Optical Microscopy and Cell Analysis Core provides advanced imaging, flow cytometry and cell sorting services to support a broad range of biological research. Our expert staff members offer hands-on technical guidance in instrument operation, experimental design and data analysis, delivering high-quality data and collaborative support to empower precise, cutting-edge science.
Flow cytometry services
The core offers state-of-the-art instrumentation for high-speed acquisition, quantitative analysis, and sorting of cells or particles in suspension using single-laser and multilaser excitation. Cell sorting services allow precise physical separation of defined subpopulations for downstream applications.
The facility houses a comprehensive suite of analyzers and sorters, including:
- BD FACSAria fusion flow cytometers.
- BD FACSCanto X clinical flow cytometry system.
- BD FACSMelody cell sorter.
- Bio-Rad ZE5 cell analyzer.
- Cytek Aurora spectral analyzer.
- LSRFortessa X-20 cell analyzer.
Data analysis workstations also are available at no cost.
The core's staff members provide expert support for experimental design, data acquisition, interpretation and user training. This includes hands-on and after-hours access.
Optical microscopy services
The core supports a wide range of microscopy modalities for high-resolution optical sectioning and 3D reconstruction, including:
- Brightfield.
- Darkfield.
- Differential interference contrast.
- Fluorescence.
- Laser scanning confocal microscopy.
- Phase contrast.
Integrated analysis software enables quantitative evaluation of digital images, including measurements of size, shape, intensity and spatial organization within cells and tissues. The core provides personalized training and technical support to help investigators:
- Plan and coordinate experiments.
- Select appropriate instrumentation.
- Navigate scheduling, billing and data storage policies.
The core ensures comprehensive support from project planning through successful execution.