Equipment and Facilities

Major instrumentation

Electron microscopy

  • JEOL JEM-1400 TEM
  • JEOL JEM-1400(Plus) TEM
  • FEI Tecnai G2 Spirit TEM
  • FEI Tecnai T12 TEM (with EDAX X-ray microanalysis detector)
  • Hitachi S-4700 FE-SEM (with Noran System 7 X-ray detector)
  • Thermo Fisher VolumeScope SBSEM

Flow cytometry and cell sorting

  • Bio-Rad ZE5 Cell Analyzer
  • BD FACSCanto
  • BD FACSCanto X SORP
  • BD LSRFortessa X-20 SORP
  • BD LSR II SORP
  • BD FACSAria IIu SORP
  • BD FACSAria II SORP
  • BD FACSMelody

Optical (light) microscopy

  • Zeiss LSM 780 confocal microscopes
  • Zeiss Axiovert 40 widefield microscope
  • Zeiss Axio Scan.Z1 digital slide scanner
  • Olympus FV1000 MPE multiphoton laser scanning microscopes
  • Zeiss Elyra PS.1 superresolution microscope
  • Wild M420 macroscope
  • Nikon Eclipse Ti inverted microscope

In addition, a wide variety of preparative equipment and computer-aided image processing and analysis workstations are available within the core.

Facilities

The Microscopy and Cell Analysis Core occupies more than 5,000 square feet, with offices and main lab space located on the 14th floor of the Guggenheim Building at Mayo Clinic's campus in Rochester, Minnesota.

In addition to being a Mayo Clinic research core, the Microscopy and Cell Analysis Core is part of the Mayo Clinic Cancer Center, which is a National Cancer Institute-designated comprehensive cancer center. The core also has strong ties with Mayo's clinical departments, including the Department of Laboratory Medicine and Pathology and Mayo Clinic Laboratories.