Clinical Trials

The purpose of this study is to evaluate prospective physician-patient agreement on the Summary Outcomes Determination (SOD) score and its ability to gauge outcomes after shoulder and elbow surgery.

The purpose of this study is to assess analgesia effectiveness between liposomal bupivacaine single injection interscalene blockade vs. continuous interscalene nerve block for patients undergoing primary total shoulder arthroplasty. It also aims to include pain scores and opioid consumption at pre-defined time intervals, peripheral nerve block complications, length of hospital stay, and postoperative follow-up up to 7 days after surgery.

The purpose of this study is to determine if peripheral nerve block with liposomal bupivacaine in combination with standard bupivacaine will prolong the duration of block, improve pain scores, and decrease opioid utilization in the post-operative period when compared to peripheral nerve block with standard bupivacaine alone.

The correlation between lymphedema and shoulder arthroplasty will be analyzed using medical records for all patients that came to the Mayo Clinic with a diagnosis of lymphedema within the time period of 1979-2016.

We will use multiple variables to analyze the associations between lymphedema and multiple other factors, including infection, recurrence of disease, implant failure, etc.

The purpose of this study is to evaluate safety and efficacy and show non-inferiority of the investigational PERFORM Stemless Reverse device to the control PERFORM Stem Reverse device in subjects who are candidates for the treatment of noninflammatory degenerative joint disease (i.e., osteoarthritis), avascular necrosis, pseudoparalysis or anterior superior escape, rotator cuff tear arthropathy, correction of functional deformity, and post-traumatic arthritis.

The purpose of this study is to:

• Evaluate the influence of the critical shoulder angle (CSA) on outcomes after total anatomic shoulder arthroplasty; and
• Evaluate the influence of the critical shoulder angle (CSA) on rotator cuff failure after total anatomic shoulder arthroplasty.

The purpose of this study is to evaluate the outcomes and complications in patients who have received a hemiarthroplasty, anatomic total shoulder, or reverse total shoulder arthroplasty.

The purpose of this study is evaluate the outcomes and complications in patients who underwent a rotator cuff repair.

The objective of the study is to determine if there is a difference in ultrasound image quality of the interscalene block anatomy, at point of care, pre- versus post-operatively in a cohort of patients undergoing shoulder arthroscopy who routinely receive blockade of the brachial plexus for postoperative analgesia.

The primary objective of this study is to collect and evaluate long-term clinical and radiographic outcomes data to better understand the safety and performance of shoulder arthroplasty over time.

Aims, purpose, or objectives

Aim 1: To quantify passive stiffness modifications due to RSA in deltoid muscle.

Aim 2: To interpret these modifications in the light of postoperative clinical outcomes.

The purpose of this study is to detect whether arm rotation (pronation vs. supination) affects glenohumeral alignment. If so, does this impact what prosthesis would be used for a shoulder arthroplasty?

This purpose of this study is to answer if patients fair better with non-operative management or reverse total arthroplasty for treatment of 3- and 4-part proximal humerus fractures.

The aim of this protocol is to determine clinical, functional, radiographic, and survival outcomes in patients undergoing an uncemented reverse total shoulder arthroplasty for a proximal humerus fracture.

The purpose of this study is to examine and report nerve injury patterns that occur during shoulder replacement. We will also look at the outcomes of these injuries over time.

The purpose of this study is to evaluate the outcomes and complications of anatomic total shoulder and reverse total shoulder arthroplasty systems using bone preserving shoulder arthroplasty system.

The purpose of the study is a multi-center prospective registry to collect clinical outcomes of anatomic and reverse total shoulder arthroplasty.

The purpose of this study is to compare the outcome of primary anatomic shoulder arthroplasty using the Stryker ReUnion system with implantation of either a peg or keel glenoid construction.

The purpose of this study is to compare the outcome of primary reverse shoulder arthroplasty using the Stryker ReUnion System with the implantation of either a large (40 mm) or a small (36 mm) glenosphere (shoulder to arm, ball shaped joint).

The purpose of this study is to to assess the clinical and radiographic outcomes of patients who have undergone shoulder arthroplasty.

The purpose of this study is to compare the effectiveness of pain control between a single shot interscalene brachial plexus nerve block, a continuous interscalene brachial plexus nerve block, and a local infiltration analgesia. Total shoulder arthroplasty is considered to be a major surgical procedure resulting in severe postoperative pain, especially in the first 48 hours after surgery. The use of interscalene brachial plexus nerve block remains the cornerstone for analgesia following shoulder surgery, however, there has been increasing interest in local infiltration analgesia use for total joint arthroplasty. The benefits of local infiltration analgesia within a comprehensive analgesia clinical pathway have yet to be ...

The purpose of this study is to to determine the impact of anesthesia (liposomal bupivacaine) on diaphragm muscle forces using a non-invasive ultrasonographic shear wave elastography (SWE) method.  

The purpose of this study is to assess the impact of a whole food plant-based diet on blood sugar control in diabetic patients versus a control group on the American Diabetics Association diet before having a total hip, knee, or shoulder replacement surgery.

The purpose of this study is to learn why there are differences between those who develop stiff joints and those who do not by examining the genes responsible for joint contractures in people who have had total joint surgery.

The purpose of this study is to evaluate the clinical outcomes, survivorship, and complications of HIV-positive patients undergoing total hip or total knee arthroplasty at the Mayo Clinic in the past 20 years.