Reverse Total Shoulder Arthroplasty versus Nonoperative Treatment of 3 & 4-Part Proximal Humerus Fractures


About this study

This purpose of this study is to answer if patients fair better with non-operative management or reverse total arthroplasty for treatment of 3- and 4-part proximal humerus fractures.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  1. Displaced 3- and 4-part proximal humerus fractures.
  2. Age greater than or equal to 65 years old.

Exclusion Criteria:

  1. Less than 65 years old.
  2. Medical comorbidities precluding surgical treatment or anesthesia.
  3. Dementia or inability to provide adequate follow up.
  4. Pathologic fractures.
  5. Open fractures.
  6. Associated injuries: fracture dislocations, multiple or complex injuries of the ipsilateral limb, complete brachial plexopathy, vascular injury and polytrauma.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Jonathan Barlow, M.D.

Closed for enrollment

More information


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