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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 32 for Ultrasound

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  • Study status: Open/Status Unknown
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  1. A Study of the Mayo Clinic College of Medicine Ultrasound System

    Rochester, MN

  2. Ultrasound Imaging of Hepatic Masse Vasculature for Treatment Evaluation

    Rochester, MN

  3. Training of Physicians in Critical Care Ultrasonography (CCUS)

    Rochester, MN

  4. New Technologies to Determine Carotid Plaque Vulnerability in Patients With Significant Carotid Plaques

    Rochester, MN

  5. Study to Compare Contrast-Enhanced Ultrasound, Contrast-Enhanced Dual Energy Mammography, and Contrast-Enhanced Breast MR for Early Breast Cancer Detection

    Rochester, MN

  6. A Study to Predict Sepsis-Associated Acute Kidney Injury by Assessing Renal Microvascular Blood Flow and Elasticity with Contrast-Enhanced Ultrasonography and Ultrasound Elastogram

    Rochester, MN

  7. A Study to Determine the Feasibility of Doppler Ultrasound of Large Arterial Systems of the Brain as Vascular Involvement Markers in Presbyacusis and Presbyvestibulopathy

    Jacksonville, FL

  8. A Study of Evaluating the Use of Ultrasound Shear Wave Imaging in Patients with Liver Fibrosis

    Rochester, MN

  9. Ultrasound Evaluation of Synovitis

    Rochester, MN

  10. A Study to Evaluate Advanced Ultrasound Techniques for Diagnosis of Giant Cell Arteritis

    Rochester, MN


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