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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-8 of 8 for Cardiac rehabilitation

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  • Study status: Open/Status Unknown
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  1. A Study of Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure that has Preserved Ejection Fraction

    Rochester, MN, Cannon Falls, MN, La Crosse, WI, Albert Lea, MN, Austin, MN, Red Wing, MN, Mankato, MN

  2. A Study to Evaluate Cardiac Rehabilitation Outcomes Through Mobile Case Management

    Rochester, MN

  3. A Study to Compare the Effectiveness of Different High-intensity Interval Training Programs in Cardiac Rehabilitation

    Rochester, MN

  4. A Study Evaluate the Positive Impact of Canine Therapy on Cardiac Rehab Patient Outcomes

    La Crosse, WI

  5. A Study to Evaluate Breathing Muscle Training in Cardiac Rehab

    Rochester, MN

  6. A Study of the Impact of Cardiac Rehabilitation after Myectomy Procedure for Hypertrophic Cardiomyopathy

    Rochester, MN

  7. A Study to Measure Physical Activity and Sedentary Behavior During Cardiac Rehabilitation

    Rochester, MN

  8. A Study to Validate Patient Self-assessment of Physiologic Outcomes in Cardiac Rehab

    Rochester, MN

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