Voice Analysis Technology to Detect and Manage Depression and Anxiety in Cardiac Rehabilitation


About this study

The purpose of this study is to evaluate the impact of interventions on important CV biomarkers to provide valuable information on the mechanism linking depression and anxiety to cardiac prognosis resulting in improved quality of life and diagnosis.



Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • ≥ 18 years.
  • Diagnosed myocardial infarction (MI).
  • Enrolled in cardiac rehabilitation program to start within 4 weeks from hospital discharge due to MI.
  • Owns a smartphone.
  • Willing to download and use a smartphone app.
  • Able to read, write, and speak English.

Exclusion Criteria:

  • Pregnancy.
  • Actively treated for an anxiety or depressive disorder through psychotherapy or pharmacologic treatments.
  • Cardiac transplant.
  • Active substance use.
  • Neurocognitive disorder.
  • Active psychosis.
  • Mania diagnosis.

Eligibility last updated 12/14/21. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Amir Lerman, M.D.

Open for enrollment

Contact information:

Preventive Heart Research Team

(507) 538-7425


More information


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