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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-5 of 5 for Heart valve surgery

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  • Study status: Open/Status Unknown
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  1. PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on Apixaban

    Rochester, MN

  2. SAPIEN M3 System TransCatheter MItral Valve ReplaCement via TransseptaL AccEss

    Rochester, MN

  3. Phase III Study to Evaluate the Efficacy and Safety of the INTERCEPT Blood System for Red Blood Cells in Patients Undergoing Complex Cardiac Surgery Procedures

    Rochester, MN

  4. Determining the Impact of Ascorbic Acid Treatment on Vasodilation in Cardiac Surgery

    Rochester, MN

  5. A Study to Evaluate Aortic Dilatation in Patients with Conotruncal Abnormalities

    Rochester, MN

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