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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 12 for

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  • Study status: Open/Status Unknown
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  1. PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on Apixaban

    Rochester, MN

  2. PARADIGM: Amplatzer Valvular Plug for PVL Closure

    Rochester, MN

  3. SAPIEN M3 System TransCatheter MItral Valve ReplaCement via TransseptaL AccEss

    Rochester, MN

  4. A Study to Analyze Rhythm Control and Potential Early Surgery for Tricuspid Regurgitation

    Rochester, MN

  5. A Study to Evaluate the Safety and Effectiveness of Beating Heart Mitral Valve Repair with the HARPOON™ System

    Rochester, MN

  6. SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial

    Rochester, MN

  7. Effect of RBT-1 on Preconditioning Response Biomarkers in Subjects Undergoing CABG and/or Cardiac Valve Surgery

    Rochester, MN

  8. A Study to Evaluate Mitral Implantation of Transcatheter Valves

    Rochester, MN

  9. A Study to Evaluate the Innovalve Transseptal Mitral Valve Replacement System to Treat Patients with Mitral Valve Regurgitation

    Rochester, MN

  10. Intraoperative Observations and Long-term Outcomes of Bioprosthetic Valve Implantation

    Rochester, MN

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