A Study to Evaluate Aortic Dilatation in Patients with Conotruncal Abnormalities

Overview

About this study

The purpose of this study is to assess operative and postoperative outcomes after aortic valve surgery, evaluate for changes in ascending aorta diameter by comparing pre-operative CT imaging to measurements on follow-up imaging, and examine late outcomes and functional status during the follow-up period with specific focus on mortality, need for re-operation and incidence of aortic dissection.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria: Adult patients (aged 18 or above) undergoing aortic valve repair or replacement with preexisting diagnosis of conotruncal abnormality including:

  • Pulmonary atresia with ventricular septal defect
  • Tetralogy of Fallot
  • Truncus arteriosus
  • Double-outlet right ventricle
  • Transposition of great arteries

Surgery to the aortic valve must have been preformed between January 1st 1973 and December 31st 2015.
Exclusion Criteria: concomitant surgery on the aortic root or ascending aorta at the time of aortic valve surgery.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Elizabeth Stephens, M.D., Ph.D.

Contact us for the latest status

Contact information:

Jessica Steadman M.B.B.S.

(507) 266-9515

Steadman.Jessica@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

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