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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 35 for

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  1. J&J Vaccine Booster in Transplant Recipients

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. Concomitant Renal and Urinary Bladder Allograft Transplantation

    Rochester, MN

  3. A Study to Evaluate NPC-21 to Treat Kidney Transplant Patients at High Risk for Cytomegalorvirus Infection

    Scottsdale/Phoenix, AZ

  4. Adipose-derived MSC to Treat Rejection in Kidney Transplant Recipients

    Rochester, MN

  5. A Study to Evaluate Posoleucel ALVR105 to Treat Kidney Transplant Recipients with BK Viremia

    Scottsdale/Phoenix, AZ

  6. Clazakizumab for the Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients (IMAGINE)

    Scottsdale/Phoenix, AZ, Rochester, MN

  7. Feasibility and Safety of Allogeneic Adipose Mesenchymal Stem Cells (aMSCs) Delivery Into Kidney Allografts Procured from Deceased Donors with High Kidney Donor Profile Index (KDPI)

    Jacksonville, FL

  8. A Safety and Efficacy Study of FCR001 vs Standard of Care in de Novo Living Donor Kidney Transplantation (FREEDOM-1)

    Rochester, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL

  9. A Study to Evaluate the Effectiveness and Safety Study of Imlifidase in Treatment of Antibody-Mediated Rejection in Kidney Transplant Patients

    Rochester, MN

  10. The Role of Genetics and Socioeconomic Factors in Outcomes After Kidney Transplantation in Hispanics and American Indians

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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