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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 28 for Kidney transplant

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  • Study status: Open/Status Unknown
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  1. Efficacy and Safety of Human Plasma-derived C1-esterase Inhibitor as add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection (AMR) in Adult Renal Transplant Recipients

    Scottsdale/Phoenix, AZ, Rochester, MN

  2. Cellular Immunotherapy in Recipients of HLA-matched, Living Donor Kidney Transplants

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. Exercise to Treat Frailty in Kidney Transplant Candidates

    Rochester, MN

  4. A Study to Evaluate the Safety and Effectiveness of Clazakizumab for the Treatment of Chronic Active Antibody-Mediated Rejection in Kidney Transplant Recipients

    Scottsdale/Phoenix, AZ, Rochester, MN

  5. A Study to Examine The Effectiveness, Feasibility, and Acceptability of Exercise Intervention on Frailty After Kidney Transplantation.

    Rochester, MN

  6. Improve Graft Function and Reduce the Severity of Kidney Dysfunction or Delayed Graft Function Following Kidney Transplantation in Recipients of a Deceased Donor Kidney

    Scottsdale/Phoenix, AZ

  7. Study of Treg Therapy in Subclinical Inflammation in Kidney Transplantation (TASK)

    Rochester, MN

  8. A Study to Evaluate the Effectiveness and Safety Study of Imlifidase in Treatment of Antibody-Mediated Rejection in Kidney Transplant Patients

    Rochester, MN

  9. A Study to Evaluate Clinical Performance of the Aptima® CMV Quant Assay on the Panther® System

    Rochester, MN

  10. A Study to Identify Physical Function Trajectories and Biomarkers after Kidney Transplantation

    Rochester, MN, Jacksonville, FL

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