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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 16 for Seizures

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  • Study status: Open/Status Unknown
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  1. A Study of the Thalamus Using Deep Electrode EEG to Better Understand its Participation in the Beginning or Spreading of Seizures

    Rochester, MN

  2. A Study to Assess Medtronic Deep Brain Stimulation (DBS) Therapy for Epilepsy Post-Approval (EPAS)

    Rochester, MN, Jacksonville, FL

  3. A Study of Lacosamide to Treat Neonatal Seizures

    Rochester, MN

  4. Study of the Incidence of Electrographic Status Epilepticus and Seizures of PICU Patients at National Children’s Hospital in Hanoi, Vietnam.

    Rochester, MN

  5. A Study of Adjunctive Ganaxolone Treatment in Children and Young Adults with CDKL5 Deficiency Disorder

    Rochester, MN

  6. A Study Evaluating the Use of 48-hour Ambulatory EEG Monitoring in Early Onset Alzheimer’s Disease

    Jacksonville, FL

  7. A Study to Evaluate an Adjunctive Anti-Seizure Medication to Treat Patients with Drug-Resistant Focal Epilepsy and High-Grade Glioma

    Jacksonville, FL

  8. Neural Circulatory Control and SUDEP Risk.

    Rochester, MN

  9. Genetic Markers of Cardiovascular Disease in Epilepsy

    Rochester, MN

  10. A Study to Evaluate Newly-diagnosed Idiopathic Generalized Epilepsy

    Rochester, MN

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