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(for at least one location)
Describes the nature of a clinical study. Types include:
The objective of this study is to determine the safety and efficacy of transcatheter aortic valve replacement (TAVR) via a transfemoral approach in HF patients with moderate AS as compared with OHFT.
Study statuses change often. Please contact us for help.
Open for enrollment
The purpose of this study is to establish the safety and effectiveness of the Edwards PASCAL Transcatheter Tricuspid Repair System in patients with symptomatic severe tricuspid regurgitation who have been determined to be at an intermediate or greater estimated risk of mortality with tricuspid valve surgery by the cardiac surgeon with concurrence by the local Heart Team.
The purpose of this study is to compare conventional assessment of systolic ventricular function on a 2D heart echo with an assessment of more immediate changes in heart mechanics using 2D and 3D measurements of deformation and strain in patients undergoing infusion of Trastuzumab for breast cancer.
The purpose of this study is to demonstrate that use of the Sentinel® Cerebral Protection System significantly reduces the risk of peri-procedural stroke (≤ 72 hours) after transcatheter aortic valve replacement (TAVR).
Contact us for the latest status
To assess the safety and effectiveness of the SAPIEN 3 (Edwards Lifesciences, Irvine, California) transcatheter heart valve in patients with a failing aortic bioprosthetic valve.
This clinical trial is a prospective, randomized, controlled, multi-center study. Patients will be randomized 1:1 to receive either transcatheter aortic valve replacement (TAVR) with the Edwards SAPIEN 3 THV or clinical surveillance. Patients will be stratified by whether or not they are able to perform a treadmill stress test. Patients who have a positive stress test will be followed in a registry to collect data on subsequent treatment and mortality, as applicable.
The purpose of this study is to determine if 3D volumetric measurements will allow more robust quantification of valvular heart disease severity.
The purpose of this study is to: investigate the diagnostic utility of stress echocardiography (SE) in the evaluation of patients with mixed and mult-valvular heart disease (mx/ml-VHD), evaluate the hemodynamic impact of exercise on mx/ml-VHD compared to those with isolated valve disease, study the prevalence and natural history of mx/ml-VHD, and identify clinical, echocardiographic and biochemical markers that can be used to identify patients with mx/ml-VHD who are at higher risk for future cardiovascular events.
The purpose of this study is to learn more about early and late outcomes in patients after mitral valve repair.
The purpose of this study is to assess the feasibility of color M mode and standard vena contracta measurements and compare these to novel measurements of aortic regurgitation in left ventricular assist devices (LVADs).
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