A Repository of Atria Tissue for the Investigation of Atrial Pathophysiology in Patients with Atrial Fibrillation


About this study

The purpose of this study is to collect surgically removed atrial tissue for genetic, pathologic, metabolic, and molecular studies in patients with or without a history of atrial fibrillation.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • A history of documented atrial fibrillation who undergo cardiac surgery for valvular heart disease or coronary artery disease with concomitant MAZE procedure
  • A history of documented atrial fibrillation including post-operative AF undergoing cardiac surgery without MAZE procedure
  • A history of atrial fibrillation undergoing cardiac surgery (controls)
  • Heart transplant recipients with AF or without AF (controls)
  • All above willing to donate surgically removed atrial tissue to the study

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Hon-Chi Lee, M.D., Ph.D.

Open for enrollment

Contact information:

Yongmei Cha M.D.



More information


Publications are currently not available

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