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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 32 for

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  1. Enhancing the Natriuretic Peptide System in HFpEF

    Rochester, MN

  2. Exercise Training to Improve Pulmonary Haemodynamic and Right Ventricular Function in Heart Failure Patients with Pulmonary Hypertension

    Jacksonville, FL

  3. Improving Cardiac Rehabilitation Outcomes Through Mobile Case Management (iCARE)

    Rochester, MN

  4. Exploratory Ph 2A, Double-Blind, Placebo-Controlled Dose Escalation Study of Safety, Tolerability, PD, & PK of HU6 for Subjects With Obese HFpEF

    Rochester, MN

  5. A Study of Sotatercept for the Treatment of Cpc-PH Due to HFpEF (MK-7962-007/​A011-16)

    Jacksonville, FL

  6. A Research Study to Look at How a New Medicine Called NNC6019-0001 Works and How Safe it is for People Who Have Heart Disease Due to Transthyretin (TTR) Amyloidosis

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. Cardiac Rehabilitation in Heart Failure With Mitochondrial Adaptation To High-intensity Interval Training

    Rochester, MN

  8. Voice Analysis Technology to Detect and Manage Depression and Anxiety in Cardiac Rehabilitation

    Rochester, MN

  9. Cardiac and Metabolic Effects of Semaglutide in Heart Failure With Preserved Ejection Fraction

    Rochester, MN

  10. A Study to Evaluate Breathing Muscle Training in Cardiac Rehab

    Rochester, MN


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