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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 33 for Epilepsy

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  • Study status: Open/Status Unknown
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  1. A Study to Assess the Effectiveness, Safety, and Tolerability of NBI-827104 in Pediatric Patients with Epileptic Encephalopathy

    Rochester, MN

  2. A Single-blind, Placebo-controlled, Outpatient Trial to Assess the Effects of Single Oral Tablet Dose of OPC-214870

    Rochester, MN

  3. A Study Evaluating the Use of 48-hour Ambulatory EEG Monitoring in Early Onset Alzheimer’s Disease

    Jacksonville, FL

  4. A Study to Evaluate an Adjunctive Anti-Seizure Medication to Treat Patients with Drug-Resistant Focal Epilepsy and High-Grade Glioma

    Jacksonville, FL

  5. A Study to Evaluate fMRI of Active DBS Stimulation in Epilepsy

    Rochester, MN

  6. Neural Circulatory Control and SUDEP Risk.

    Rochester, MN

  7. Genetic Markers of Cardiovascular Disease in Epilepsy

    Rochester, MN

  8. A Study of Mood Symptoms in Epilepsy Patients

    Rochester, MN

  9. A Study to Evaluate Newly-diagnosed Idiopathic Generalized Epilepsy

    Rochester, MN

  10. A Study to Examine the Natural History of Infants and Children with SCN1A-positive Dravet Syndrome

    Rochester, MN

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