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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 57 for

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  1. REstrictive versus LIberal Rate of Extracorporeal Volume Removal Evaluation in Acute Kidney Injury (RELIEVE-AKI)

    Rochester, MN

  2. Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease

    Rochester, MN

  3. A Study to Evaluate the Safety, Tolerability and Effectiveness of V117957 in Subjects with Insomnia Associated with Alcohol Cessation

    Rochester, MN

  4. A Study to Evaluate the Effectiveness and Safety of RalinEpag for Improving Treatment Outcomes in PAH Patients

    Jacksonville, FL

  5. A Study to Evaluate the Effectiveness and Safety of Remdesivir to Treat Coronavirus Disease 2019 in an Outpatient Setting

    Rochester, MN

  6. A Study to Assess Neuromuscular Ultrasound to Predict the Duration of Mechanical Ventilation.

    Rochester, MN

  7. A Study to Evaluate Oxygen Supplementation Duration to Assess Resolution of Acute Hypoxic Respiratory Failure

    Rochester, MN

  8. COVID-19 and Acute Renal Failure

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  9. Influence of Immunosuppresion on Lung Iron Content in Pneumonia

    Scottsdale/Phoenix, AZ

  10. Synucleinopathies

    Rochester, MN

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