Influence of Immunosuppresion on Lung Iron Content in Pneumonia


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Scottsdale/Phoenix, Arizona: 12-005717
    Sponsor Protocol Number: 12-005717

About this study

The purpose of the study is to see whether lung concentrations of iron and a protein that binds iron are influenced by the presence of pneumonia. Increased amounts of iron in the lungs may promote the growth or microorganisms and may influence the severity of lung injury caused by an infection. We are comparing the amount of iron that accumulates in the lungs in response to pneumonia in different types of patients.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

Inclusion Criteria:

  • Subjects will be recruited from patients undergoing flexible fiberoptic bronchoscopy for the clinical purpose of evaluating for possible pneumonia with bronchoalveolear lavage (BAL). 
  • Informed consent will be obtained prior to the procedure.  

Exclusion Criteria:

  • Subjects will not be recruited if they are intubated or are located in the intensive care unit. 

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Lewis Wesselius, M.D.

Contact us for the latest status

Contact information:

Vy Nguyen CCRP


More information


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Study Results Summary

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Supplemental Study Information

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