Influence of Immunosuppresion on Lung Iron Content in Pneumonia


About this study

The purpose of the study is to see whether lung concentrations of iron and a protein that binds iron are influenced by the presence of pneumonia. Increased amounts of iron in the lungs may promote the growth or microorganisms and may influence the severity of lung injury caused by an infection. We are comparing the amount of iron that accumulates in the lungs in response to pneumonia in different types of patients.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Subjects will be recruited from patients undergoing flexible fiberoptic bronchoscopy for the clinical purpose of evaluating for possible pneumonia with bronchoalveolear lavage (BAL). 
  • Informed consent will be obtained prior to the procedure.  

Exclusion Criteria:

  • Subjects will not be recruited if they are intubated or are located in the intensive care unit. 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Lewis Wesselius, M.D.

Contact us for the latest status

Contact information:

Vy Nguyen CCRP

(480) 342-1328

More information


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