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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. Valchlor in the Treatment of Lichen Planopilaris

    Jacksonville, FL

  2. Study of Encorafenib + Cetuximab Plus or Minus Binimetinib vs. Irinotecan/Cetuximab or Infusional 5-Fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab With a Safety Lead-in of Encorafenib + Binimetinib + Cetuximab in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer

    Jacksonville, FL, Rochester, MN, Scottsdale/Phoenix, AZ

  3. Development of a Risk Index for Prediction of Health Outcomes and Healthcare Utilization

    Rochester, MN

  4. An Extension Study to Assess the Safety of the Use of Cannabidiol in Children and Young Adults with Dravet or Lennox-Gastaut Syndromes

    Scottsdale/Phoenix, AZ

  5. A Study of GDC-0134 to Determine Initial Safety, Tolerability, and Pharmacokinetic Parameters in Participants With Amyotrophic Lateral Sclerosis

    Jacksonville, FL

  6. A Study of Quality of Life and Pain Control Before and After Endovascular Renal Denervation in Individuals with Refractory Kidney Pain

    Rochester, MN

  7. Treatment of RLS/WED Symptoms Through Sensory Counter-stimulation

    Rochester, MN

  8. Early Coronary Angiography Versus Delayed Coronary Angiography

    Rochester, MN

  9. A Study to Evaluate the Safety and Effect of CFZ533 on Patients with Graves' Disease

    Rochester, MN

  10. A Study of Using Lorvotuzumab Mertansine in Treating Younger Patients with Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma

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