Learning More about How your Brain Works with Decreased Levels of Oxygen


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 16-004354
    Sponsor Protocol Number: 16-004354

About this study

The specific aim of this proposal is (1) to develop a human model of hypoxia in which cerebrovascular reactivity and cognitive function can be simultaneously measured and (2) develop pilot data in our laboratory on the relationship between cerebrovascular reactivity and cognitive function during three different hypoxic conditions with and without addition of inspired CO2 as a mechanism to maintain cerebral blood flow.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria

  • Adult male and female, 18-35 years of age;

  • Able to understand the study, and having understood, provide written informed consent in English

  • Subject must be in general good health as determined by medical history, physical exam and by physician investigator

  • If female and of child bearing potential, have a negative pregnancy test prior (within 48 hours) to participating in the study.


Exclusion Criteria:

  • Subject is unable or unwilling to participate in all aspects of the study.

  • Females who are pregnant

  • Significant medical history including neurological disease, learning disability or cognitive dysfunction, pulmonary disease, or cardiovascular disease


Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Timothy Curry, M.D., Ph.D.

Open for enrollment

Contact information:

Shelly Roberts R.N.


More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

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