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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. Fall Recovery Training for Older Adults in Continuous Care Facilities

    Rochester, MN

  2. Pilot Study: Combined Molecular Breast Imaging/Ultrasound System for Diagnostic Evaluation of MBI-detected Lesions

  3. Pazopanib Hydrochloride in Treating Patients With Metastatic Kidney Cancer Who Have No Evidence of Disease After Surgery

    Rochester, MN

  4. S0820, Adenoma and Second Primary Prevention Trial

    Rochester, MN

  5. A Study to Find Out the Best Treatment for Walled-off Pancreatic Necrosis

    Rochester, MN

  6. Bathing Additives in Pediatric Atopic Dermatitis

    Rochester, MN

  7. A Study of the Effectiveness of Educational Preparation for the Caregivers of Blood and Bone Marrow Transplant Patients , to Relieve Their Feelings of Stress

    Rochester, MN

  8. Efficacy and Safety Study of Orvepitant for Chronic Cough in Patients With Idiopathic Pulmonary Fibrosis

    Rochester, MN

  9. Effects of Energy Drinks on Sleep and Cardiovascular Health

    Rochester, MN

  10. Safety and Efficacy of Investigational Anti-Influenza Immune Plasma in Treating Influenza

    Rochester, MN

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